IACUC Protocol Preparation Tools & Aids

Pre-Review Guide for Investigators

• Commensal Antigen-Specific T cells
• Genetic Control of Inflammatory Responses
• Thoracic Allograft Tolerance in Non-Human Primates
• Tibia fracture model with plate fixation

1. Flow Chart Requirements – A detailed guide to flow chart content
2. Flow Chart Checklist – A tool that can be used during flow chart preparation
3. Flow Chart Examples
   
   These examples are not required flow chart templates but are intended to serve as useful guides for flow chart design.  Each can be downloaded and edited to fit the specifics of your study.

1. Breeding Studies
2. Drug Treatment and Tissue Collection Timeline
3. Multiple Pain Categories
4. NHP Transplant
5. Rodent Surgery and Imaging Timeline
6. Tumor Production and Drug Treatment

1. Pain Management Regimens for Mice and Rats
2. Anesthesia and Pain Management Regimens for Small Ruminants
3. Anesthesia and Pain Management Regimens for Swine
4. Anesthesia and Pain Management Regimens for Rabbits
5. Guidelines for Assigning Pain and Distress Categories 

1. Sample Size Calculations for Animal Research – the following tools can be used to determine minimum sample size:
   •  Sample Size Calculations in Animal Research  (W. W. LaMorte, BUMC)
   • ClinCalc Sample Size Calculator
   • Jackson Laboratories Breeding Colony Size Planning Worksheet
2.  The 3 Rs ~ Replacement, Reduction, Refinement ~ Alternatives Literature Search